Cerebrovascular Disease and Mechanisms of Cognitive Impairment
نویسندگان
چکیده
منابع مشابه
Subclinical cerebrovascular disease in mild cognitive impairment.
BACKGROUND Cerebrovascular disease (CVD) may contribute to mild cognitive impairment (MCI). We sought to determine the relation of white matter hyperintensity (WMH) volume and infarcts in brain MRI to MCI in a community-based sample. METHODS A total of 679 elderly persons without dementia underwent brain MRI. WMH and infarcts were quantified using research methods. WMH was adjusted for total ...
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C erebrovascular disease (CVD) is an important cause of disability and dementia. Accumulating evidence from clinical, neuroimaging, and pathological studies indicates a durable link between CVD and cognitive impairment. To distinguish this relationship, over the years various disorders have been progressively refined to include arteriosclerotic dementia, multi-infarct dementia, vascular dementi...
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We tried to evaluate and to compare usefulness of two brief cognitive tests in early detection of cognitive decline in subjects with increased cerebrovascular (CV) risk. As CV risk factors are recognised as important in etiology of dementia, we also aimed to determine the possible associations of specific CV risk factors and cognitive results. Patients (PGs) with first-ever stroke or TIA (N=110...
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Similar manifestations of functional decline in ageing and Alzheimer's disease obscure differences in the underlying cognitive mechanisms of impairment. We sought to examine the contributions of top-down attentional and bottom-up perceptual factors to visual self-movement processing in ageing and Alzheimer's disease. We administered a novel heading discrimination task requiring subjects to dete...
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demonstrated significantly more severe SVD-associated pathology compared to controls, which suggests that SVD may have a role in the pathophysiology of PD [12]. Another longitudinal study by Foo et al. demonstrated that progression of SVD was associated with significant cortical thinning in the frontoparietal regions with concomitant decline in memory, executive functions, and motor functions i...
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ژورنال
عنوان ژورنال: Stroke
سال: 2012
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.112.655803